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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T28017 |
Merbarone
RLBN-1001,NSC-336628,RLBN1001,NSC336628 |
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Merbarone is a Type II DNA topoisomerase inhibitor. Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage. Merbarone induces activation of caspase-activated DNase and excision of chromosomal DNA loops from the n |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01236 |
DFFB Protein, Human, Recombinant (His)
DNA fragmentation factor 40 kDa subunit,Caspase- |
Human | E. coli |
Nuclease that induces DNA fragmentation and chromatin condensation during apoptosis. Degrades naked DNA and induces apoptotic morphology. |